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Gabapentin

Created
07/05/2009

Last edit: Alan Hope
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A widely used analgesic - particularly for neuropathic pain.

Structurally mimics GABA, but mode of action on neuropathic pain is thought to be due to the blocking of voltage-gated Ca++ channels.

It is well tolerated and excreted unmetabolised. Drowsiness and peripheral oedema are the commonest side-effects.

gabapentin.jpg
    
2 tag(s)
Pharmacology
Pain relief